Course details
Course description
Explore how robust variant interpretation is needed to support patients with increased risk of cancer.
Explore germline variation in cancer susceptibility genesGermline genomic variation can increase the risk of developing cancer. It’s essential to use the best evidence available to decide if a genomic variant is likely to increase the chance of a person developing cancer. This allows us to offer at-risk individuals access to appropriate screening, prevention, and personalised treatments.
Learn how to interpret genes for susceptibility to cancerOn this course, you will consider how variant interpretation in cancer susceptibility genes has different considerations when compared with variant interpretation in rare paediatric disease.
You’ll explore the guidelines produced by the UK Cancer Variant Interpretation Group (CanVIG-UK) for variant interpretation and how these can be applied to the American College of Medical Genetics (ACMG) framework in the classification of germline variants in cancer susceptibility genes.
Study the CanVIG-UK guidelines in theory and practiceThis course will provide you with patient examples to explore the complexities of variant interpretation in cancer genomics. You’ll also hear from experts in the field about how the CanVIG-UK guidance was created.
You’ll be encouraged to apply your learning through case-based exercises that illustrate both the strengths and weaknesses of the tools and guidelines available for cancer variant interpretation.
Study with world-leading genomic experts at St George’sLearn from Professor Kate Tatton-Brown and Dr Katie Snape – renowned consultant Clinical Geneticists leading on variant interpretation for rare disease and cancer.
This course is part of a series with Interpreting Genomic Variation: Fundamental Principles.
What topics will you cover?- Inherited genetic variation in familial cancer syndromes.
- Tools for variant interpretation and how these are applied to the interpretation of cancer susceptibility gene variation.
- The application of the ACMG framework to inherited cancer.
- The implementation of a clinical framework to embed cancer susceptibility gene interpretation into clinical practice.
Entry requirements
This course would be suitable for:
• Clinical Genetics doctors (consultant and specialist registrars) • Clinical Scientists • Genetic Counsellors • Clinical Oncology doctors (consultants and specialist registrars) • Pathologists undertaking cancer MDTs • Specialist oncology nurses undertaking genetic testing
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Course details
Online
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Cost: £0.00 (ex. VAT)
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